Hyperdermoclysis (clysis) is the subcutaneous infusion of fluids for rehydration and dehydration. This method of fluid infusion is beneficial in the hospice setting where many patients are thin with poor venous access and/or poor oral access.
Normal saline is administered via gravity fed tubing with a subcutaneous catheter. The infusion rates range from 20 to 125ml/hour. Up to 2 liters can be given per site per day.
Most adverse effects — such as edema, pain, discomfort or leaking — can be alleviated by moving the injections site. Immediately discontinue if any signs of infection or fluid overload occur.
Walsh, Gabrielle. “Hypodermoclysis: An Alternate Method for Rehydration in Long‐term Care.” Journal of Infusion Nursing 28.2 (2005): 123-129.